Samantha N. McNulty, PhD

Instructor, Pathology & Immunology

Additional Titles

  • Project Manager, Genomics and Pathology Services

Related Links


  • BS, Biology (Summa Cum Laude): St. Louis University, St. Louis, MO (2005)
  • PhD, Molecular Microbiology and Microbial Pathogenesis: Washington University School of Medicine, St. Louis, MO (2012)

Research Interests

Dr. McNulty received her PhD in Molecular Microbiology and Microbial Pathogenesis from the Washington University School of Medicine in 2012 for work characterizing the genetic interplay between filarial nematodes and Wolbachia endobacteria. During her postdoctoral training at the McDonnell Genome Institute, she gained extensive experience in the production, curation, and integration of high-throughput genomic, transcriptomic and proteomic data. She has participated in several multinational projects aimed at developing diagnostic tools for parasitic infections that have large-scale impacts on global health, particularly in the developing world. In her current role as a Project Coordinator at GPS, Dr. McNulty provides bioinformatics support and assists in the development of novel sequence-based diagnostic assays. She is eager to integrate the latest sequencing technologies and bioinformatics tools into routine clinical care.


Carter JH, McNulty SN, Cimino PJ, Cottrell CE, Heusel JW, Vigh-Conrad KA, Duncavage EJ. Targeted Next-Generation Sequencing in Molecular Subtyping of Lower-Grade Diffuse Gliomas: Application of the World Health Organization’s 2016 Revised Criteria for CNS Tumors. J Mol Diagn. 2016 Dec 30. pii: S1525-1578(16)30259-8. PMID: 28042970.
Lee PJ, McNulty S, Duncavage EJ, Heusel JW, Hagemann IS. Clinical Targeted Next-Generation Sequencing Shows Increased Mutational Load in Endometrioid-type Endometrial Adenocarcinoma With Deficient DNA Mismatch Repair. Int J Gynecol Pathol. 2017 Oct 27. PMID: 29084048.
Carter JH, Cottrell CE, McNulty SN, Vigh-Conrad KA, Lamp S, Heusel JW, Duncavage EJ. FGFR2 Amplification in Colorectal Adenocarcinoma. Cold Spring Harb Mol Case Stud. 2017 Nov 21;3(6). PMID: 28835367.
Nemeth K, Szabo S, Cottrell CE, McNulty SN, Segura A, Sokumbi O, Browning M, Siegel DH. Mosaic pathogenic HRAS variant in a patient with nevus spilus with agminated Spitz nevi and parametrial-uterine rhabdomyosarcoma. Br J Dermatol. 2017 Nov 28. PMID: 29193020.
Rosenbaum JN, Bloom R, Armstrong J, Hiken J, Branson J, McNulty SN, Pepin K, Abel H, Cottrell CE, Pfeifer JD, Kulkarni S, Govindan R, Konnick EQ, Lockwood CM, Duncavage EJ. Genomic Heterogeneity of ALK Fusion Breakpoints in Non-Small Cell Lung Cancer. Mod Pathol. 2018 May. PMID 29327716.
Alberti MO, Srivatsan SN, Shao J, McNulty SN, Chang GS, Miller CA, Dunlap JB, Yang F, Press RD, Gao Q, Ding L, Heusel JW, Duncavage EJ, Walter MJ. Discriminating a common somatic ASXL1 mutation (c.1934dup; p.G646Wfs*12) from artifact in myeloid malignancies using NGS. Leukemia. 2018 Aug. PMID: 29959414.


Lori Scantlan