Deyali Chatterjee, MD

Assistant Professor, Pathology & Immunology

Education

  • Residency, Anatomic Pathology: Baylor College of Medicine, Houston, TX (2016)
  • Fellowship, GI and Liver Pathology: MD Anderson Cancer Center, Houston, TX, 2017 (2017)

Clinical Interests

  • Liver pathology
  • GI & Pancreas pathology

Research Interests

I have a strong interest in clinicopathologic and collaborative research in the field of pancreatobiliary and gastrointestinal pathology. I have studied various histopathologic aspects after neoadjuvant therapy in pancreatic ductal adenocarcinoma and have also studied pancreatic histology of mouse models, including xenografts for pancreatic cancer.

Publications

Peer-reviewed original research

  1. Chatterjee D, Katz MH, Foo WC, Sundar M, Wang H, Varadhachary GR, Wolff RA, Lee JE, Maitra A, Fleming JB, Rashid A, Wang H. Prognostic Significance of New AJCC Tumor Stage in Patients with Pancreatic Ductal Adenocarcinoma Treated with Neoadjuvant Therapy. Am J Surg Pathol. 2017 Aug;41(8):1097-1104.
  2. Roland CL, Starker LF, Kang Y, Chatterjee D, Estrella J, Rashid A, Katz MH, Aloia TA, Lee JE, Dasari A, Yao JC, Fleming JB. Loss of DPC4/SMAD4 expression in primary gastrointestinal neuroendocrine tumors is associated with cancer-related death after resection. Surgery. 2017 Mar;161(3):753-759.
  3. Gomez-Chou SB, Swidnicka-Siergiejko A, Badi N, Chavez-Tomar M, Lesinski GB, Bekaii-Saab T, Farren MR, Mace TA, Schmidt C, Liu Y, Deng D, Hwang RF, Zhou L, Moore TT, Chatterjee D, Wang H, Leng X, Arlinghaus RB, Logsdon CD, Cruz-Monserrate Z. Lipocalin-2 Promotes Pancreatic Ductal Adenocarcinoma by Regulating Inflammation in the Tumor Microenvironment. Cancer Res. 2017 May 15;77(10):2647-2660.
  4. Chadha AS, Skinner HD, Gunther JR, Munsell MF, Das P, Minsky BD, Delclos ME, Chatterjee D, Wang H, Clemons M, George G, Singh PK, Katz MH, Fleming JB, Javle MM, Wolff RA, Varadhachary GR, Crane CH, Krishnan S. Phase I Trial of Consolidative Radiotherapy with Concurrent Bevacizumab, Erlotinib and Capecitabine for Unresectable Pancreatic Cancer. PLoS One. 2016 Jun 23;11(6):e0156910.
  5. Kang Y, Roife D, Lee Y, Lv H, Suzuki R, Ling J, Rios Perez MV, Li X, Dai B, Pratt M, Truty MJ, Chatterjee D, Wang H, Thomas RM, Wang Y, Koay EJ, Chiao PJ, Katz MH, Fleming JB. Transforming Growth Factor-β Limits Secretion of Lumican by Activated Stellate Cells within Primary Pancreatic Adenocarcinoma Tumors. Clin Cancer Res. 2016 Apr 28. [Epub ahead of print]
  6. Xia M, Overman MJ, Rashid A, Chatterjee D, Wang H, Katz MH, Fleming JB, Lee JE, Varadhachary GR, Wolff RA, Wang H. Expression and clinical significance of epidermal growth factor receptor and insulin-like growth factor receptor 1 in patients with ampullary adenocarcinoma. Hum Pathol. 2015 Sep;46(9):1315-22.
  7. Ayala G, Frolov A, Chatterjee D, He D, Hilsenbeck S, Ittmann M. Expression of ERG protein in prostate cancer: variability and biological correlates. Endocr Relat Cancer. 2015 Jun;22(3):277-87.
  8.  Roland CL, Yang AD, Katz MH, Chatterjee D, Wang H, Lin H, Vauthey JN, Pisters PW, Varadhachary GR, Wolff RA, Crane CH, Lee JE, Fleming JB. Neoadjuvant Therapy is Associated with a Reduced Lymph Node Ratio in Patients with Potentially Resectable Pancreatic Cancer. Ann Surg Oncol. 2015 Apr;22(4):1168-75.
  9. Kang Y, Zhang R, Suzuki R, Li SQ, Roife D, Truty MJ, Chatterjee D, Thomas RM, Cardwell J, Wang Y, Wang H, Katz MH, Fleming JB. Two-dimensional culture of human pancreatic adenocarcinoma cells results in an irreversible transition from epithelial to mesenchymal phenotype. Lab Invest. 2015 Feb;95(2):207-22.
  10. Li X, Truty MA, Kang Y, Chopin-Laly X, Zhang R, Roife D, Chatterjee D, Lin E, Thomas RM, Wang H, Katz MH, Fleming JB. Extracellular lumican inhibits pancreatic cancer cell growth and is associated with prolonged survival after surgery. Clin Cancer Res. 2014 Dec 15;20(24):6529-40
  11. Thomas RM, Truty MJ, Kim M, Kang Y, Zhang R, Chatterjee D, Katz MH, Fleming JB. The Canary in the Coal Mine: The Growth of Patient-Derived Tumorgrafts in Mice Predicts Clinical Recurrence after Surgical Resection of Pancreatic Ductal Adenocarcinoma. Ann Surg Oncol. 2015;22(6):1884-92.
  12. Kang Y, Ling J, Suzuki R, Roife D, Chopin-Laly X, Truty MJ, Chatterjee D, Wang H, Thomas RM, Katz MH, Chiao PJ, Fleming JB. SMAD4 regulates cell motility through transcription of N-cadherin in human pancreatic ductal epithelium. PLoS One. 2014 Sep 29;9(9):e107948
  13. Wang H, Estrella JS, Chatterjee D, Katz MH, Rashid A, Wang H, Wolff RA, Varadhachary GR, Lee JE, Pisters PW, Abbruzzese JL, Fleming JB. Hepatobiliary/Pancreas Pathology: SY11-3 pancreatic ductal adenocarcinoma: neoadjuvant therapies and pathology. Pathology. 2014 Oct; 46 Suppl 2:S25
  14. Koay EJ, Baio F, Ondari A, Truty MJ, Cristini V, Thomas RM, Chen R, Chatterjee D, Kang Y, Zhang J, Court L, Bhosale PR, Tamm EP, Qayyum A, Crane CH, Javle M, Katz M, Gottumukkala VN, Rozner MA, Shen H, Lee JE, Wang H, Chen Y, Plunkett WK, Abbruzzese JL, Wolff RA, Maitra A, Ferrari M, Varadhachary G, Fleming J. Intra-tumoral heterogeneity of gemcitabine delivery and mass transport in human pancreatic cancer. Physical biology. 2014 Nov 26;11(6)
  15. Guo R, Shroff S, Rashid A, Chatterjee D, Varadhachary G, Abbruzzese JA, Katz MHG, Fleming JB, Wang H. Aberrant expression of p53, p21, cyclin D1 and Bcl2 and their clinicopathologic correlation in ampullary adenocarcinoma. Human Pathology. 2014 May;45(5):1015-23
  16. Koay EJ, Truty MJ, Cristini V, Chen R, Thomas RM, Chatterjee D, Kang Y, Bhosale PR, Tamm EP, Crane CH, Javle M, Katz MH, Gottumukkala VN, Rozner MA, Shen H, Lee JE, Wang H, Chen R, Plunkett WK, Abbruzzese JL, Wolff RA, Varadhachary GR, Ferrari M, Fleming JB. Transport properties of pancreatic cancer describe gemcitabine delivery and response. Journal of Clinical Investigation. 2014;124(4):1525–1536
  17. Thong JF, Chatterjee D, Hwang SY. Endoscopic modified Lothrop approach for the excision of bilateral frontal sinus tumors. Ear Nose Throat J. 2014 Mar;93(3):116-9.
  18. Philip B, Roland CL, Daniluk J, Liu Y, Chatterjee D, Gomez SB, Ji B, Huang H, Wang H, Fleming JB, Logsdon CD, Cruz-Monserrate Z. A high-fat diet activates oncogenic Kras and COX2 to induce development of pancreatic ductal adenocarcinoma in mice. Gastroenterology. 2013 Dec;145(6):1449-58.
  19. Chatterjee D, Katz MH, Rashid A, Estrella J, Wang H, Varadhachary GR, Wolff RA, Lee JE, Pisters PW, Abbruzzese JL, Fleming JB, Wang H. Pancreatic Intraepithelial Neoplasia and Histologic Changes in Benign Pancreas Associated with Neoadjuvant Therapy in Patients with Pancreatic Ductal Adenocarcinoma. Histopathology. 2013 Dec;63(6):841-51
  20. Shroff S, Overman MJ, Rashid A, Shroff RT, Wang H, Chatterjee D, Katz MH, Lee JE, Wolff RA, Abbruzzese JL, Fleming JB, and Wang H. The Expression of PTEN Is Associated With Improved Prognosis in Patients With Ampullary Adenocarcinoma After Pancreaticoduodenectomy. Archives of Pathology & Laboratory Medicine 2013 Nov;137(11):1619-26.
  21. Chang Z, Li Z, Kang Y, Niu J, Wang H, Chatterjee D, Fleming J, Abbruzzese J, Chiao P. Deciphering the mechanisms of tumorigenesis in human pancreatic ductal epithelial cells. Clinical Cancer Research. 2013 Feb 1;19(3):549-59.
  22. Weng S, Wang H, Chen W, Katz MH, Chatterjee D, Lee JE, Pisters PW, Gomez HF, Abbruzzese JL, Fleming JB, Wang H. Overexpression of Protein Phosphatase 4 Correlates with Poor Prognosis in Patients with Stage II Pancreatic Ductal Adenocarcinoma. Cancer Epidemiology Biomarkers and Prevention. 2012 Aug; 21(8):1336-43.
  23. Chatterjee D, Katz MH, Rashid A, Varadhachary GR, Wolff RA, Wang H, Lee JE, Pisters PW, Vauthey JN, Crane C, Gomez HF, Abbruzzese JL, Fleming JB, Wang H. Histologic grading the extent of residual carcinoma following neoadjuvant chemoradiation in pancreatic ductal adenocarcinoma: A predictor for patient outcome. Cancer. 2012 Jun; 118(12):3182-90
  24. Chatterjee D, Rashid A, Wang H, Katz MH, Wolff RA, Varadhachary GR, Lee JE, Pisters PW, Gomez HF, Abbruzzese JL, Fleming JB, Wang H. Tumor invasion of muscular vessels predicts poor prognosis in patients with pancreatic ductal adenocarcinoma who have received neoadjuvant therapy and pancreaticoduodenectomy. American Journal of Surgical Pathology. 2012 Apr; 36(4):552-9.
  25. Chatterjee D, Katz MH, Rashid A, Wang H, Iuga AC, Varadhachary GR, Wolff RA, Lee JE, Pisters PW, Crane CH, Gomez HF, Abbruzzese JL, Fleming JB, Wang H. Perineural and intraneural invasion in posttherapy pancreaticoduodenectomy specimens predicts poor prognosis in patients with pancreatic ductal adenocarcinoma. American Journal of Surgical Pathology. 2012 Mar; 36(3):409-17.
  26. Puvanakrishnan P, Park J, Chatterjee D, Krishnan S, Tunnell JW. In vivo tumor targeting of gold nanoparticles: effect of particle type and dosing strategy. International Journal of Nanomedicine. 2012 Mar; 7:1251-8.
  27. Lee J, Ng C, Chatterjee D. Cytomegalovirus colitis presenting as massive lower gastrointestinal bleeding in an immunocompetent patient. Indian Journal of Surgery. 2008 Feb; 70(1):28-31

Invited Editorials and Commentaries

Chatterjee D. Liquid biopsies: handle with care. Pathol Lab Med Open J. 2016; 1(1): 3-6.

Case Reports, Technical Notes, Letters

Chatterjee D, Wang H. Mixed Adenoneuroendocrine Carcinoma Arising in a Papillary Adenoma of Gallbladder. American Journal of Cancer Case Reports. 2014 Vol 2, No 1 (2014):37-42

Chapter, Notes and Reviews

Chatterjee D, Finch C. Sclerosing Thymoma. Arch Pathol Lab Med. 2015 Aug; 139(8):1068-70.


Assistant
Billie Charlton
314-273-1742
billie.charlton@wustl.edu

Office Location: BJC-IH Building, Room 3434