LGM – History

In the early 1970s, trainees in laboratory medicine were challenged to integrate new computer technology and automation into the hospital laboratory environment. The results are the highly automated, high-throughput medical laboratories operating today. In the early 1980s, clinical pathologists utilized monoclonal antibody technology originally developed in the basic science laboratory to develop numerous new medical tests in endocrinology, cardiology and oncology. In the 1990s, the recognition of new pathogens and human identification of the genes associated with disease processes lead to the development of new molecular assays to effectively monitor and treat patients.

The sequencing of the human genome and the genomes of many pathogens has ushered in the era of genomics in diagnostic clinical medicine. Gene sequencing and microarray technology are now central approaches in diagnostic clinical pathology. We expect the 21st century to bring new clinical tests centered on epigenomics and proteomics, and we plan on being at the forefront of test development and application using these approaches. In addition, new recombinant antibody technologies will make multiplexed, ultra-sensitive and nanotechnology immuno-based assays possible that will revolutionize the field. Future trainees in laboratory and genomic medicine may expect to further the field of medical laboratory diagnostics in many exciting ways.

Learn more about the history of the Department.