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Philip Ahern, PhD

Instructor, Pathology & Immunology



  • BSc in Industrial Biochemistry: University of Limerick, Limerick, Ireland (2004)
  • D. Phil. (PhD): University of Oxford, Oxford, UK (2009)


  • Henry Wellcome Postdoctoral Fellowship

Research Interests

Mucosal immunology, microbiota, immune tolerance, autoimmunity, inflammation, T cells

Editorial Responsibilities

Ad hoc Reviewer Mucosal Immunology
Ad hoc Reviewer Proceedings of the National Academy of Sciences (PNAS)


Griffin NW, Ahern PP, Cheng J, Heath AC, Ilkayeva O, Newgard CB, Fontana L, Gordon JI. Prior Dietary Practices and Connections to a Human Gut Microbial Metacommunity Alter Responses to Diet Interventions. Cell Host Microbe., 2017 Jan 11;21(1):84-96
Ahern PP*, Faith JJ*, Gordon JI. Mining the human gut microbiota for effector strains that shape the immune system. Immunity, 2014 Jun 19;40(6):815-23. *equal contribution
Faith JJ*, Ahern PP*, Ridaura VK, Cheng J, Gordon JI. Identifying gut microbe-host phenotype relationships using combinatorial communities in gnotobiotic mice.  Sci Transl Med., 2014 Jan 22;6(220):220ra11. *equal contribution
Kau AL*, Ahern PP*, Griffin NW, Goodman AL, Gordon JI. Human nutrition, the gut microbiome and the immune system. Nature, 2011 Jun 15; 474(7351):327-36. *equal contribution
Ahern PP*, Schiering C*, Buonocore S, McGeachy MJ, Cua DJ, Maloy KJ, Powrie F. Interleukin-23 drives intestinal inflammation through direct activity on T cells. Immunity, 2010 Aug 27;33(2):279-88. *equal contribution
Buonocore S, Ahern PP, Uhlig HH, Ivanov II, Littman DR, Maloy KJ and Powrie F. Innate lymphoid cells drive interleukin-23 dependent innate intestinal pathology. Nature, 2010 Apr 29;464(7293):1371-5
Ahern PP, Izcue A, Maloy KJ and Powrie F. The interleukin-23 axis in Intestinal Inflammation. Immunological Reviews, 2008, Dec;226;147-59
Hue S, Ahern P, Buonocore S, Kullberg MC, Cua DJ, McKenzie BS, Powrie F and Maloy KJ. Interleukin-23 drives innate and T cell-mediated intestinal inflammation. J Exp Med., 2006 Oct 30;203(11):2473-83

Lab phone: 314-362-0978
Office Location: 4515 McKinley Avenue