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Leslie McIntosh, PhD

Assistant Professor, Pathology & Immunology



Additional Titles

  • Director, Center for Biomedical Informatics


  • BA, Biology: Texas A&M, College Station, TX (1993)
  • MPH, Public Health: Biostatistics & Epidemiology: St. Louis University, St. Louis, MO (2006)
  • PhD, Public Health Epidemiology: St. Louis University, St. Louis, MO (2008)

Research Interests

My current research focuses on how to develop and utilize both large (i.e. hundreds of terabytes) and heterogeneous (i.e., thousands of variables from multiple sources) health data to provide meaningful decision support for effective and efficient health care delivery and research. Currently, I serve as the Director of the Center for Biomedical Informatics at Washington University School of Medicine and am the Director of the Siteman Cancer Center Biomedical Informatics Core overseeing over 20 individuals providing informatics research, service, infrastructure, and operational support.


McIntosh L. Internet Data Collection.  In:  Boslaugh S., editor.  Encyclopedia of Epidemiology.  Thousand Oaks, California:  Sage Publishing, 2007.
Santosh V, McIntosh L. E-learning Networks Projects:  Tracking Youth Attitudes, Opinions, & Beliefs with Network Text Analysis.  Final report submitted and accepted by March, 2007.
Baker EA, Brownson RC, Dreisinger M, McIntosh LD, Karamehic-Muratovic A. Examining the roll of training in evidence-based public health:  a qualitative study.  Health Promot Pract. 2009 Jul; 10(3):342-8. doi:  1177/1524839909336649.  PMID:  19574586 [PubMed – indexed for MEDLINE]
McIntosh LD. The structural assessment of the SF-36 in respondents of the Medicare Health Outcomes Survey to gauge health-related quality of life.  Saint Louis University.    Available from:
Shimoyama M, Nigam R, McIntosh LS, Nagarajan R, Rice T, Rao DC, Dwinell MR. Three ontologies to define phenotype measurement data.  Fron Genet.  2012 May 28:3:87.  doi:  3389/ fgene. 2012.00087. eCollection 2012.  PMID:  22654893; PMCID:  PMC3361058
Davis V, Holmes KL, Lowe BJ, McIntosh L, Tomich L, Miggio A. Implementing VIVO and Filling IT with Life.  In:  Borner K, et al.  VIVO:  A Semantic Approach to Scholarly Networking and Discovery.  October 2012.  doi:  2200/S00428ED1V01Y201207WBE002
Wright SJ, Kozlowski WA, Dietrich D, Khan HJ, Steinhart GS, McIntosh L. Using Data Curation Profiles to Design the Datastar Dataset Registry.  D-Lib Magazine.  July/Aug 2013.  doi:  1045/july2013-wright
Cottrell CE, Al-Kateb H, Bredemeyer AJ, Duncavage EJ, Spencer DH, Abel HJ, Lockwaood CM, Hagemann IS, O’Guin SM, Burceau LC, Sawyer CS, Oschwald DM, Stratman JL, Sher DA, Johnson MR, Brown JT, Cliften PF, George B, McIntosh LD, Shrivastava S, Nguyen TT, Payton JE, Watson MA, Crosby SD, Head RD, Mitra RD, Nagarajan R, Kulkarni S. Seibert K, Virgin HW 4th, Milbrandt J, Pfeifer JD. Validation of a next-generation sequencing assay for clinical molecular oncology.  J Mol Diagn.  2014 Jan; 16(1):89-105.  Epub 2013 Nov 6.  PMID:  24211365
McIntosh LD, Zabarovskaya K, Uhlmansiek M. It’s Just (Academic) Business:  Improving Informatics Operations with Business Intelligence. AMIA Jt Summits Transl Sci Proc.  2015 Mar 25;2015:117-21.  eCollection 2015.  PMID:  26306252
Mcintosh LD, Sharma MK, Mulvihill D, Gupta S, Juehne A, George B, Khot SB, Kaushal A, Watson MS, Nagarajan R. caTissue suite to Open Specimen:  Developing an extensible, open source, web-based biobanking management system.  J Boimed Inform. N 2015 Aug 29.  Pii: S1532-0464(15)00188-4. PMID:  26325296
McIntosh LD, Mulvihill D, Govindrao P, Gupta S, Juehne A, George B, Kalantri P, Adiga S, Watson M, Nagarajan R. caTissue Suite:  An extensible, web-based database application for biospecimen data management. Journal of biomedical informatics 57 (2015): 456-464.
McIntosh LD, Zabarovskaya. Visualizing Operational Analytics in Biomedical Informatics.  AMIA CRI. 2015 AMIA Joint Summits on Translational Science Proceedings.
McIntosh LD, Zabarouskaya K,. Uhlmansiek M. It’s Just (Academic) Business:  A Use Case in Improving Informatics Operations with Business Intelligence.  AMIA Summits on Translational Science Proceedings, 2015, p. 117.

Lori Scantlan

Office Location: Cortex Building, Suite 302