Shaw Lab Publications

2007 2006 2005 2004

2007

Cemerski S, Das J, Locasale J. Arnold P, Giurisato E, Markiewicz MA, Fremont D, Allen PM, Chakraborty AK, Shaw AS.  The stimulatory potency of T cell antigens is influenced by the formation of the immunological synapse.  Immunity 2007;26:345-355
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Locasale JW, Shaw AS, Chakraborty AK.  Scaffold proteins confer diverse regulatory properties to protein kinase cascades.  Proc Natl Acad Sci 2007;104:13307-13312.
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Akilesh S, Christianson GJ, Roopenian DC, Shaw AS.  Neonatal FcR expression in bone marrow-derived cells functions to protect serum IgG from catabolism.  J Immunol 2007;179:4580-4588.
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Giurisato E, Cella M, Takai T, Kurosaki T, Feng Y, Longmore GD, Colonna M, Shaw AS.  Phosphatidylinositol 3-kinase activation is required to form the NKG2D immunological synapse.  Mol Cell Biol 2007;27:8583-8599.
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Akilesh S, Koziell A, Shaw, AS.  Basic science meets clinical medicine: Identification of a CD2AP deficient patient.  Kidney Int 2007;72:1181-1183.  Click to View

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2006

Huber TB, Kwoh C, Wu H, Asanuma K, Godel M, Hartleben B, Blumer KJ, Miner JH, Mundel P, Shaw AS.  Bigenic mouse models of focal segmental glumerulosclerosis involving pairwise interaction of CD2AP, Fyn, and synaptopodin.  J Clin Invest 2006;116:1337-1345
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Bruck S, Huber TB, Ingham RJ, Kim K, Niederstrasser H, Allen PM, Pawson T, Cooper JA, Shaw AS.  Identification of a novel inhibitory actin-capping protein binding motif in CD2 associated protein.  J Biol Chem 2006;281:19196-19203
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Kortum RL, Johnson HJ, Costanzo DL, Volle DJ, Razidlo GL, Fusello ASM, Shaw AS, Lewis RE.  The molecular scaffold kinase suppressor of Ras 1 is a modifier of RasV12-induced and replicative senescence.  Mol Cell Biol 2006;26:2202-2214
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Woroniecki RP, Schiffer M, Shaw AS, Kaskel FJ, Bottinger EP.  Glomerular expression of transforming growth factor-beta (TGF-beta) isoforms in mice lacking CD2-associated protein.  Pediatr Nephrol 2006;21:333-338
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Jarad G, Cunningham J, Shaw AS, Miner JH.  Proteinuria precedes podocyte abnormalities in Lamb2-/- mice, implicating the glomerular basement membrane as an albumin barrier.  J Clin Invest 2006;116:2272-2279
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Graham DB, Cella M, Guirisato E, Fujikawa K, Miletic AV, Kloeppel T, Brim K, Takai T, Shaw AS, Colonna M, Swat W.  Vav1 controls DAP10-medicated natural cytoxicity by regulating actin and microtubule dynamics.  J Immunol 2006;177:2349-2355
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Blasius AL, Guirisato E, Cella M, Schreiber RD, Shaw AS, Colonna M.  Bone marrow stromal cell antigen 2 is a specific marker of Type I IFN-producing cells in the naïve mouse, but a promiscuous cell surface antigen following IFN stimuation.  J Immunol 2006;177:3260-3265.
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Fusello AM, Mandik-Nayak L, Shih F, Volle DJ, Lewis RE, Allen PM, Shaw AS.  The MAPK scaffold kinase suppressor of Ras is involved in ERK activation by stress and proinflammatory cytokines and induction of arthritis.  J Immunol 2006;177:6152-6158
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Shaw AS.  Lipid rafts: now you see them, now you don’t.  Nat Immunol 2006;7:1139-1142.
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2005

Burack WR, Shaw AS.  Live cell imaging of ERK and MEK: simple binding equilibrium explains the regulated nucleocytoplasmic distribution of ERK.  J Bio Chem. 2005;280:3832-38237
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Kim JM, White JM, Shaw AS, Sleckman BP.  MAPK p38 alpha is dispensable for lymphocyte development proliferation.  J Immunol 2005;174:1239-1244
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Grunkemeyer JA, Kwoh C, Huber TB, Shaw AS.  CD2-associated protein (CD2AP) expression in podocytes rescues lethality of CD2AP deficiency.  J Biol Chem 2005;280:29677-29681
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Welsch T, Endlich N, Gokce G, Doroshenko E, Simpson JC, Kriz W, Shaw AS, Endlich K.  Association of CD2AP with dynamic actin on vesicles in podocytes.  Am J Physiol Renal Physiol 2005;289:F1134-1143
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Markiewicz MA, Carayannopoulos LN, Naidenko OV, Matsui K, Burack WR, Wise ER, Fremont DH, Allen PM, Yokoyama WM, Colonna M, Shaw AS.  Costimulation through NKG2D enhances murine CD8+ CTL function: similarities and differences between NKG2D and CD28 costimulation.  J Immunol 2005;175:2825-2833

Lin J, Shaw AS.  Getting downstream without a raft.  Cell 2005:815-816.
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Lin J, Miller MJ, Shaw AS.  The c-SMAC: sorting it all out (or in).  J Cell Biol 2005;170:177-182
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Shaw AS.  T-cell activation and immunologic synapse.  Immunol Res 2005;32:247-252.
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2004

Fuchs A, Cella M, Guirisato E, Shaw AS, Colonna M.  Cutting edge: ED96 (tactile) promotes NK cell-target cell adhesion by interacting with the poliovirus receptor (CD155).  J Immunol 2004;172:3994-3998 
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  • Pizzo P, Giurisato E, Bigste, A, Tassi M, Tavano R, Shaw A, Viola A.  Physiological T cell activation starts and propagates in lipid rafts.  Immunol Lett 2004; 91:3-9 http://www.ncbi.nlm.nih.gov/sites/entrez
  • Schiffer M, Mundel P, Shaw AS, Bottinger EP.  A novel role for the adaptor molecule CD2-associated protein in transforming growth factor-beta-induced apoptosis.  J Biol Chem 2004;279:37004-37012 Click to View


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