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The American College of Surgeons Oncology Group (ACOSOG) is a clinical trial cooperative group supported publicly by the National Cancer Institute (NCI).

The Tissue Procurement Core (TPC) at Washington University School of Medicine is the Central Specimen Bank (CSB) for the American College of Surgeons Oncology Group.  At present, specimens have been collected in a total of 16 different studies.  Seven of these studies are being actively collected.

ACOSOG focuses on the effects of surgery on patients with malignant tumors.