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Faculty > Faculty By Appointment > Frances White, MD

Associate Professor, Pathology and Immunology
Associate Professor, Pediatrics
Section Head, Pediatric Pathology
Room 300S, Peters Building
Office: (314) 362-0147
E-mail: fwhite@wustl.edu
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Research

Dr. White’s research interests in pediatric pathology are focused on medical liver and lung disease. She also has a strong interest in gastrointerstinal diseases including Hirschsprung disease. She is a member of the Biliary Atresia Research Consortium, Cholestatic Liver Disease Consortium and the Children’s Interstitial Lung Disease Network.

Service to the Department

PresentHead of Perinatal and Pediatric Autopsy Service Barnes Hospital and St. Louis Childrens Hospital

Diagnostic Expertise

Dr. White's clinical interests and diagnostic expertise are in pediatric neoplastic and non-neoplastic disease. She heads the Pediatric Autopsy Service and the Electron Microscopy Laboratory and is involved in perinatal autopsies and pediatric surgical

Clinical Interest

Anatomic and Molecular Pathology - Electron Microscopy
Anatomic and Molecular Pathology - Autopsy Pathology
Anatomic and Molecular Pathology - Pediatric Pathology

Selected Publications

Sainathan SK, Hanna EM, Gong Q, Bishnupuri KS, Luo Q, Colonna M, White FV, Croze E, Houchen C, Anant S, Dieckgraefe BK. Granulocyte macrophage colony-stimulating factor ameliorates DSS-induced experimental colitis. Inflammatory Bowel Diseases 14:99-99, 2008

Gail H. Deutsch, Lisa R. Young, Robin R. Deterding, Leland L. Fan, Sharon D. Dell, Judy A. Bean, Alan S. Brody, Lawrence M. Nogee, Bruce C. Trapnell, Claire Langston, Eric A. Albright, Frederic B. Askin, Peter Baker, Pauline M. Chou, Carlyne M. Cool, Susa. Diffuse Lung Disease in Young Children. Am J Respir Crit Care Med 176:1120-1128, 2007

Shteyer E, Ramm GA, Xu C, White FV, Shepherd RW. Outcome after portoenterostomy in biliary atresia: pivotal role of degree of liver fibrosis and intensity of stellate cell activation. J Pediatr Gastroenterol Nutrition 42:93-99, 2006

Garmany TH, Moxley MA, White FV, Dean M, Hull WM, Whitsett JA, Nogee LM, Hamvas A. Surfactant composition and function in patients with ABCA3 mutations. Pediatr Res 59:801-805, 2006

Langston C, Patterson K, Dishop MK, child Pathology Cooperative Group: Askin F, Baker P, Chou P, Cool C, Coventry S, Cutz E, Davis M, Deutsch G, Galambos C, Pugh J, Wert S, White F. A Protocol for the Handling of Tissue Obtained by Operative Lung Biopsy: Recommendations of the chILD Pathology Co-operative Group. Pediatr and Develop Path 9:173-180, 2006

Loren DJ, Campos Y, d'Azzo, Wyble L, Grange DK, Gilbert-Barness E, White FV, Hamvas A. Sialodosis presenting as severe nonimmne fetal hydrops is associated with two novel mutations in lysosomal alpha-neuraminidase. J Perinatol 25:491-494, 2005

Weerasooriya VS, White FV, Shepherd RW. Hepatic fibrosis and survival in biliary atresia. J Pediatr 144:123-125, 2004

Hamvas A, Nogee LM, White FV, Schuler P. Progressive lung disease and surfactant dysfunction with deletion of surfactant protein C gene. Am J Respiratory Cell Mol Biol 30:771-776, 2004

White FV, Dehner LP. Viral diseases of the liver in Children. Diagnostic and differential diagnostic considerations. Pediatr Dev Pathol 7:552-567, 2004

Wright JD, Powell MA, Horowitz NS, Huettner PC, White F, Herzog TJ. Placental site trophoblastic tumor presenting with a pneumothorax during pregnancy. Obstet Gynecol 100:1141-1144, 2002 Abstract

Molleston JP, White F, Teckman J, Fitzgerald J. Obese children with steatohepatitis can develop cirrhosis in childhood. Am J Gastroenterol 97:2460-2462, 2002 Abstract

Guirgis MF, White FV, Dunbar JA, Smith ME, Lueder GT. Optic nerve teratoma and odontogenic dermoid cyst in a neonate with persistent fetal vasculature. Arch Opthalmol 120:1582-1585, 2002 Abstract

De La Morena M, Sweet S, White F, Mendeloff E, McBride G, Huddleston C, Shapiro S, Schootman M. Pediatric lung transplantation and CMV pneumonitis: a ten year experience. J Heart Lung Transplant 20:221, 2001 Abstract

Chin A, Stich D, White FV, Radhakrishnan J, Holterman MJ. Paraneoplastic pemphigus and bronchiolitis obliterans associated with a mediastinal mass: A rare case of Castlemans disease with respiratory failure requiring lung transplantation. J Pediatr Surg 36:E22, 2001 Abstract

Merchak A, Lueder GT, White FV, Cole FS. Alveolar capillary dysplasia with misalignment of pulmonary veins and anterior segment dysgenesis of the eye: a report of a new association and review of the literature. J Perinatol 21:327-330, 2001 Abstract

Volpert D, White F, Finegold MJ, Molleston J, Debaun M, Perlmutter DH. Outcome of early hepatic portoenterostomy for biliary atresia. J Pediatr Gastroenterol Nutr 32:265-269, 2001 Abstract

Dunbar AE 3rd, Wert SE, Ikegami M, Whitsett JA, Hamvas A, White FV, Piedboeuf B, Jobin C, Guttentag. Prolonged survival in hereditary surfactant protein B (SP-B) deficiency associated with a novel splicing mutation. Pediatr Res 48:275-282, 2000 Abstract

White FV, Langer JC. Circumferential distribution of ganglion cells in the transition zone of children with Hirschsprung disease. Pediatr Dev Pathol 3:216-222, 2000 Abstract

Hill DA, Dehner LP, White FV, Langer JC. Gliomatosis peritonei as a complication of a ventriculoperitoneal shunt: case report and review of the literature. J Pediatr Surg 35:497-499, 2000 Abstract

Lowichik A, White FV, Timmons CF, Weinberg AG, Gunasekaran TS, Nathan K, Coffin CM. Bannayan-Riley-Ruvalcaba syndrome: spectrum of intestinal pathology including juvenile polyps. Pediatr Dev Pathol 3:155-161, 2000

White FV, Dehner LP, Belchis DA, Conard. Congenital disseminted maligant rhabdoid tumor. A distinct clinicopathologic entity demonstrating abnormalities of chromosome 22q11. Am J Surg Pathol 23:249-256, 1999 Abstract

Lowell JA, Shenoy S, Ghalib R, Caldwell C, White FV, Peters M, Howard TK. Liver transplantation after jejunoileal bypass for morbid obesit. J Am Coll Surg 185:123-127, 1997

Coffin CM, Rulon J, Smith L, Bruggers C, White FV. Pathologic features of rhabdomyosarcoma before and after treatment: A clinicopathologic and immunohistochemical analysis. Modern Pathol 10:1175-1187, 1997

White FV, Reyes J, Jaffe R, Yunis EJ. Pathology of intestinal transplantation in children. Am J Surg Pathol 19:687-698, 1995 Abstract

Rothenberg ME, White FV, Chilmonczyk B, Chatila T. A syndrome involving immunodeficiency. Immunodeficiency 5:171-178, 1995 Abstract

White FV, Anthony DC, Yunis EJ, Tarbell NJ, Scott RM, Schofield DE. Non-random chromosomal gains in pilocytic astrocytomas of childhood. Human Pathol 26:979-986, 1995 Abstract

White FV, Jordan J, Dickman PS, Knisely AS. Fetal parvovirus B19 infection and liver disease of antenatal onset in an infant with Ebstein[]s anomaly. Pediatr Pathol and Laboratory Med 15:121-129, 1995

White FV, Anthony DC, Yunis EJ, Tarbell NJ, Scott RM, Schofield DE. Non random chromosomal gains in pilocytic astrocytomas of childhood. Human Pathol 26:979-986, 1995

Rothenberg ME, White FV, Chilmonczyk B, Chatila T. A syndrome involving immunodeficiency and multiple intestinal atresias. Immunodeficiency 5:171-178, 1995

White FV, Reyes J, Jaffe R, Yunis EJ. Pathology of intestinal transplantation in children. Am J Surg Pathol 19:687-98, 1995