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Research > Faculty Alphabetical > Peter A. Humphrey, MD, PhDLadenson Professor, Pathology and Immunology
Professor of Urologic Surgery
Head, Division of Anatomic and Molecular Pathology
Surgical Pathologist-in-Chief, Barnes-Jewish Hospital
3rd Floor, Peters Building
Office: (314) 362-0112
E-mail: humphrey@wustl.edu
Pub Med Search |  |
Research
| | The primary focus of my research is on urologic malignancies in general and specifically on prostate adenocarcinoma. At the clinicopathologic level, investigations on the surgical pathology of the prostate gland are performed including morphometric analysis of prostate cancer, studies on prostatic intraepithelial neoplasia, a putative precancerous proliferation, and histomorphologic studies on prostate cancer and its variants. Gene discovery and marker discovery in potential prostate cancer precursors and prostatic carcinoma are being pursued via gene expression profiling and whole genome sequencing.
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Editorial Responsibilities
| | 2009 - 2011 | Member, Editorial Board | Human Pathology | | 2009 - 2011 | Member, Editorial Board | Annals of Diagnostic Pathology | | Present | Associate Editor | American Journal of Clinical Pathology | | Present | Member, Editorial Board | The American Journal of Surgical Pathology | | Present | Member, Editorial Board | Modern Pathology |
Service to the Department
| | Present | Chief of Anatomic & Molecular Pathology | | Present | Member, Resident Selection Committee |
Service to the University
| | Present | Medical Student (2nd Year) Lectures on prostate cancer, bladder diseases, testis diseases |
Diagnostic Expertise
| | Urological pathology, especially urological malignancies, including prostate cancer, bladder cancer, kidney cancer, and testis cancer |
Clinical Interest
| | Anatomic and Molecular Pathology - Molecular Pathology | | Anatomic and Molecular Pathology - Urologic Pathology |
Selected Publications
| | Hameed O, Humphrey PA.. Pseudoneoplastic mimics of prostate and bladder carcinomas.. Arch Pathol Lab Med 2010; 134:427-443., 2010 Abstract
| | Cao D, Kibel AS, Gao F, Tao Y, Humphrey PA.. The Gleason score of tumor at the margin in radical prostatectomy is predictive of biochemical recurrence.. Am J Surg Pathol 2010; 34:459-463., 2010 Abstract
| | Yaskiv O, Cao D, Humphrey PA.. Microcystic adenocarcinoma of the prostate. A variant of pseudohyperplastic and atrophic patterns.. Am J Surg Pathol 2010; 34:556-561., 2010 Abstract
| | Cao D, Li J, Guo CC, Allan RW, Humphrey PA.. SALL4 is a novel diagnostic marker for testicular germ cell tumors.. Am J Surg Pathol 2009;33:1065-1077., 2009 Abstract
| | Sanati S, Watson MA, Salavaggione AL, Humphrey PA.. Gene expression profiles of ductal versus acinar adenocarcinoma of the prostate.. Mod Pathol 2009; 22:1273-1279., 2009 Abstract
| | Song H, Zhang B, Watson MA, Humphrey PA, Lim H, Milbrandt J.. Loss of Nkx3.1 leads to activation of discrete downstream target genes during prostate tumorigenesis.. Oncogene 2009; 28:3307-3319., 2009 Abstract
| | Serrano MF, Katz M, Yan Y, Kibel AS, Humphrey PA. Percentage of high-grade renal cell carcinoma as a prognostic indicator in renal cell carcinoma.. Cancer 2008; 113: 477-483., 2008 Abstract
| | Wild PJ, Giedl J, Stoehr R, Junker K, Boehm S, van Oers JMM, Zwartoff EC, Blaszyk H, Fine SW, Humphrey PA, Dehner LP, Amin MB, Epstein JI, Hartmann A. Genomic aberrations are rare in urothelial neoplasms of patients 19 years or younger. J Pathol. 2007 Jan;(1)211:18-25, 2007 Abstract
| | Turbiner J, Amin MB, Humphrey PA, Srigley JR, De Leval L, Radhakrishanan A, Oliva, E. Cystic nephroma and mixed epithelial and stromal tumor of kidney : A detailed clinicopathologic analysis of 34 cases and proposal for renal epithelial and stromal tumor (REST) as a unifying term. Am J Surg Pathol. 2007 Apr;31(4):489-500, 2007 Abstract
| | Humphrey PA. Diagnosis of adenocarcinoma in prostate needle biopsy tissue. J Clin Pathol 60:34-42, 2007 Abstract
| | Humphrey PA, Halabi S, Picus J, Sanford B, Vogelzang NJ, Small EJ, Kantoff PW. Prognostic significance of plasma scatter factor/hepatocyte growth factor levels in patients with metastatic hormone-refractory prostate cancer : Results from Cancer and Leukemia Group B 150005/9480. Clin Genitourinary Cancer 4 : 269-274, 2006 Abstract
| | Gokden N, Roehl KA, Catalona W, Humphrey PA. High-grade prostatic intraepithelial neoplasia in needle biopsy as a risk factor for detection of adenocarcinoma : Current level of risk in a screening population. Urology 65:538-542, 2005 Abstract
| | Humphrey PA. Gleason grading and prognostic factors in carcinoma of the prostate. Mod Pathol 17:292-306, 2004 Abstract
| | Thorson P, Swanson P, Vollmer RT, Humphrey PA. Basal cell hyperplasia in the peripheral zone of the prostate. Mod Pathol 16:598-606, 2003 Abstract
| | Bismar TA, Lewis JS Jr., Vollmer RT, Humphrey PA. Multiple measures of carcinoma extent versus perineural invasion in prostate needle bipsy tissue in prediction of pathologic stage in a screening population.. Am J Surg Pathol 27:432-440, 2003 Abstract
| | Hu Y, Ippolito JE, Garabedian EM, Humphrey PA, Gordon JI. Molecular characterization of a metastatic neuroendocrine cancer arising in the prostates of transgenic mice.. J Biol Chem 227:44462-44474, 2002 Abstract
| | Vollmer RT, Humphrey PA. The relative importance of anatomic and PSA factors to outcomes after radical prostatectomy for prostate cancer.. Am J Clin Pathol 116:864-870, 2001 Abstract
| | Naughton M, Picus J, Zhu X, Catalona WJ, Vollmer RT, Humphrey PA.. Scatter factor/hepatocyte growth factor elevation in the serum of prostate cancer patients.. J Urol 165:1325-1328, 2001 Abstract
| | Abdulkadir SA, Qu Z, Garabedian E, Song SK, Peters TJ, Svaren J, Carbone JM, Naughton CK, Catalona W. Impaired prostate tumorigenesis in Egr-1 deficient mice.. Nature Med 7:101-107, 2001 Abstract
| | Gokden N, Nappi O, Swanson PE, Pfeifer JD, Vollmer RT, Wick MR, Humphrey PA. Renal cell carcinoma with rhabdoid features. Am J Surg Pathol 24:1329-1338, 2000 Abstract
| | Humphrey PA, Kaleem Z, Swanson PE, Vollmer RT. Pseudohyperplastic prostatic adenocarcinoma. Am J Surg Pathol 22:1239-1246, 1998 Abstract
| | Garabedian EM, Humphrey PA, Gordon JI. A transgenic mouse model of metastatic prostate cancer originating from neuroendocrine cells. Proc Natl Acad Sci 95:15382-15387, 1998 Abstract
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