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Research > Faculty Alphabetical > Eynav Klechevsky, PhDAssistant Professor, Pathology and Immunology
Office Suite C/8417, (Room 8411 inside suite), 8th floor, BJCIH
Office: 314-286-0897
Lab: 314-747-6688
E-mail: EKlechevsky@path.wustl.edu
Pub Med Search |  |
Research
| | Our research is focused on human Dendritic cells (DCs), a specialized family of antigen presenting cells that elicit immunity to infections and tolerance to self. DCs are composed of subsets endowed with unique functional properties. Using cellular and molecular techniques we study the mechanisms by which distinct human DC subsets control immunity and tolerance, and use this information to devise immune strategies for therapeutic intervention in chronic conditions such as cancer and autoimmunity.
***One research technician position is available***
please send your CV or contact us for more information |
DBBS Graduate Program Affiliation
| | Immunology |
Selected Publications
| | Banchereau, J., Thompson-Snipes, L., Zurawski, S., Blanck, J.P., Cao, Y., Clayton, S., Gorvel, J.P., Zurawski, G., Klechevsky, E.. The differential production of cytokines by human Langerhans Cells and dermal CD14+ DCs controls CTL priming. Blood. Jun 14;119(24):5742-9., 2012 Abstract
| | Banchereau, J., Zurawski, S., Thompson-Snipes, L., Blanck, J.P., Clayton, S., Munk, A., Cao, Y., Wang, Z., Khandelwal, S., Hu, J., McCoy, W.H. 4th, Palucka, K.A., Reiter, Y., Fremont, D.H., Zurawski, G., Colonna, M., Shaw, A.S., Klechevsky, E.. Immunoglobulin-like transcript receptors on human dermal CD14+ dendritic cells act as a CD8-antagonist to control cytotoxic T cell priming. Proc Natl Acad Sci USA. Nov 13;109(46):18885-90., 2012 Abstract
| | Ueno H, Klechevsky E, Schmitt N, Ni L, Flamar AL, Zurawski S, Zurawski G, Palucka K, Banchereau J, Oh S.. Targeting human dendritic cell subsets for improved vaccines. Semin Immunol. Feb;23(1):21-7., 2011 Abstract
| | Klechevsky E, Flamar AL, Cao Y, Blanck JP, Liu M, O. Cross-priming CD8+ T cells by targeting antigens to human dendritic cells through DCIR. Blood. Sep 9;116(10):1685-97., 2010 Abstract
| | Klechevsky E, Liu M, Morita R, Banchereau R, Thompson-Snipes L, Palucka AK, Ueno H, Banchereau J.. Understanding human myeloid dendritic cell subsets for the rational design of novel vaccines. Hum Immunol. May;70(5):281-8., 2009 Abstract
| | Klechevsky E, Morita R, Liu M, Cao Y, Coquery S, Thompson-Snipes L, Briere F, Chaussabel D, Zurawski G, Palucka AK, Reiter Y, Banchereau J, Ueno H.. Functional specializations of human epidermal Langerhans cells and CD14+ dermal dendritic cells. Immunity. Sep 19;29(3):497-510., 2008 Abstract
| | Ueno H, Klechevsky E, Morita R, Aspord C, Cao T, Matsui T, Di Pucchio T, Connolly J, Fay JW, Pascual V, Palucka AK, Banchereau J.. Dendritic cell subsets in health and disease. Immunol Rev. Oct;219:118-42. Review., 2007 Abstract
| | Klechevsky E, Kato H, Sponaas AM.. Dendritic cells star in Vancouver. J Exp Med. Jul 4;202(1):5-10., 2005 Abstract
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