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Chief

Sleckman, Barry

Associate Chief

Eby, Charles


Al-Kateb, Hussam

Amarasinghe, Gaya

Amarillo, Ina

Anderson, Neil

Barratt, Michael

Blinder, Morey

Bredemeyer, Andrea

Brown, Sarah

Burnham, Carey-Ann

Calderon, Boris

Chang, Li-Wei

Cottrell, Catherine

Dantas, Gautam

Despotis, George

Dunne, Michael

Edelson, Brian

Gordon, Jeffrey

Gronowski, Ann

Grossman, Brenda

Haldar, Malay

Handley, Scott

Heusel, Jonathan

Hsiao, Ansel

Jackups, Ronald

Koues, Olivia

Kulkarni, Shashikant

Ladenson, Jack

Leung, Daisy

Lockwood, Christina

McIntosh, Leslie

Mito, Yoshiko

Mohanakumar, Thalachallour

Mosammaparast, Nima

Nagarajan, Rakesh

Oltz, Eugene

Parikh, Bijal

Payton, Jacqueline

Reyes, Alejandro

Scott, Mitchell

Seibert, Karen

Spencer, David

Swamidass, Joshua

Swat, Wojciech

Wang, David

Watson, Mark

Zhao, Guoyan


  Barry Sleckman, MD, PhD
      Conan Professor of Pathology and Immunology

      Chief of Division of Laboratory and Genomic Medicine
ContactWeb Link

Dr. Sleckman joined the LGM Division in 2005 and became the director in 2008. He is also the Co-Medical Director of the Clinical Immunology Laboratory. Dr. Sleckmanís laboratory is focused on understanding the genetic programs that promote normal lymphocyte development and on the cellular responses to and repair of DNA damage.

  Charles Eby, MD
      Professor of Pathology and Immunology
ContactWeb Link

Dr. Eby joined the LGM Division in 1991 and became Associate Chief of the LGM Division in 2011. Dr. Eby is also Director of the Hematology and Hemostasis Laboratories at Barnes-Jewish Hospital. Dr. Ebyís research is in the genetic contribution to variability of warfarin dosing through analysis of SNPs in cytochrome 2C9, VKOR and coagulation factors VII and II genes. Dr. Ebyís laboratory also studies molecular risk factors for venous thromboembolic events and acquired functional iron deficiency in cancer patients receiving recombinant erythropoietin.

  Hussam Al-Kateb, MSc, PhD, FACMG
      Assistant Professor of Pathology and Immunology

      Medical Director, Genomics & Pathology Services (GPS)
ContactWeb Link

Dr. Al-Kateb joined the LGM Division in November 2010 as an Assistant Professor of Pathology and Immunology, and an Associate Director of the Cytogenomics Lab. He became Medical Director, Genomics and Pathology Services (GPS) in 2013. He is a Training Director for the Washington University ABMG Fellowship Program. Dr. Al-Katebís research interest has been in the discovery of disease genes for both monogenic and complex disorders, and in developing genetic/genomic tests for a variety of diseases using state-of-the-art technologies. Dr. Al-Kateb is also interested in discovering prognostic markers in cancer.

  Gaya Amarasinghe, PhD
      Assistant Professor of Pathology and Immunology

      Assistant Professor of Biochemistry and Molecular Biophysics
ContactWeb Link

Dr. Gaya Amarasinghe joined the LGM Division as an Assistant Professor of Pathology and Immunology in November 2011. His current research interests include the use of biochemical and structural methods to characterize viral immune evasion strategies and host responses.

  Ina Amarillo, PhD FACMG
      Assistant Professor of Pathology and Immunology

      Associate Medical Director of Cytogenomics Laboratory
ContactWeb Link

Dr. Ina Amarillo joined the LGM Division in 2013. She is an Associate Medical Director of Cytogenomics Laboratory and an Assistant Professor of the Department of Pathology. Her clinical research interests are focused on the genetics, genomics and epigenetics of Disorders of Sex Development (DSDs) and Gonadoblastoma. She is also interested in studying the genetics, psychosocial and mental health of transgender individuals.

  Morey Blinder, MD
      Professor of Medicine

      Professor of of Pathology and Immunology
ContactWeb Link

Dr. Blinder joined the LGM Division in 1990. He is the Medical Director of Wohl Hematology Laboratory and an Associate Member of the Siteman Cancer Center. Dr. Blinderís research interests include the diagnosis and treatment of red blood cell disorders as well as platelet and coagulation abnormalities. His laboratory is developing alternative assays to aid in the management of anticoagulant dosing for patients with thromboembolic disease.

  Sarah Brown, PhD
      Assistant Professor of Pediatrics

      Assistant Professor of Pathology and Immunology
ContactWeb Link

Dr. Sarah Brown joined the LGM division in September 2011 after completing the Clinical Chemistry Fellowship at Washington University. She is the Assistant Medical Director of the Core Laboratory and the Medical Director of Ancillary Services at St. Louis Childrenís Hospital. Her research interests are in the area of pediatric pharmacology and toxicology. Sarah is also involved in global health care and laboratory quality initiatives.

  Carey-Ann Burnham, PhD
      Assistant Professor of Pathology and Immunology

      Assistant Professor of Pediatrics
ContactWeb Link

Dr. Carey-Ann Burnham joined the LGM Division in July 2009. Burnham is an Assistant Professor of Pathology & Immunology and Pediatrics at Washington University, and Medical Director of Clinical Microbiology for Barnes Jewish Hospital. She is the program director for the Washington University Fellowship in Clinical and Public Health Microbiology. Her research interests include transmission and epidemiology of Staphylococcus aureus and Clostridium difficile, MALDI-TOF MS methods for Clinical Microbiology, and antimicrobial resistance.

  Boris Calderon, MD
      Assistant Professor of Pathology and Immunology
ContactWeb Link

Dr. Calderon joined the LGM division in 2010 after completing the Clinical Chemistry Fellowship program here at Washington University. His research is focused on Type 1 Diabetes, especially in the antigen presenting cells (dendritic cells) that normally inhabit the islets of Langerhans, their migration and the early amplification of the autoimmune cellular response. Dr. Calderon is also actively involved in the Clinical Immunology Laboratory at Washington University.

  Li-Wei Chang, DSc
      Instructor of Pathology and Immunology
ContactWeb Link

Dr. Chang joined the LGM Division in 2010. His research interests are in the development of computational methods and algorithms for inferring transcriptional and post-transcriptional gene regulatory networks through integration of multiple genomic profiling datasets.

  Catherine Cottrell, PhD, FACMG
      Assistant Professor of Pathology and Immunology

      Assistant Professor of Genetics
Medical Director of Genomics & Pathology Services
ContactWeb Link

Dr. Catherine Cottrell joined the LGM Division in 2011. She is the Medical Director of Genomics and Pathology Services. Dr. Cottrellís research has primarily focused on the development of clinical testing strategies for the detection of mutations or copy number alterations in human disease. She has a specific interest in the detection of alterations in prognostically important genes related to the development and/or relapse of hematologic malignancy. She is also interested in the development of next-generation sequencing methodologies to support clinical testing.

  Gautam Dantas, PhD
      Assistant Professor of Pathology and Immunology

      Assistant Professor of of Biomedical Engineering
ContactWeb Link

Dr. Gautam Dantas joined the LGM Division as an Assistant Professor of Pathology and Immunology and a member of the Center for Genome Sciences in August 2009. His research interests lie at the interface of microbial genomics and biochemistry, synthetic biology and structural biology, with a specific focus on understanding microbial reservoirs of antibiotic resistance and in engineering microbial catalysis of plant biomass into value chemicals.

  George Despotis, MD
      Associate Professor of Pathology and Immunology

      Associate Professor of Anesthesiology
ContactWeb Link

Dr. Despotis joined the LGM Division in 1997. He is Chair of the Barnes-Jewish Hospital Transfusion Committee. Dr. Despotisí research interests are in the validation of point-of-care coagulation and platelet function instruments with respect to accuracy, reproducibility and ability to identify patients at risk for bleeding. His clinical interests reside within blood banking and transfusion medicine.

  Michael Dunne, PhD
      Adjunct Professor of Pathology and Immunology
ContactWeb Link

Dr. Dunne joined the LGM Division in 2000. He was the Medical Director of Barnes-Jewish Hospital Clinical Microbiology Laboratory and the Director of the Medical and Public Health Microbiology Fellowship until 2011 when he took a position as Executive Director of Research and Development for North America at bioMerieux, Inc. He is responsible for overseeing projects involving the development and clinical trials of diagnostic microbiology systems. Dr. Dunne will remain on faculty as an Adjunct Professor of Pathology and Immunology.

  Brian Edelson, MD, PhD
      Assistant Professor of Pathology and Immunology
ContactWeb Link

Dr. Edelson joined the LGM Division in 2011. His laboratory is focused on understanding how the innate immune system defends against microbial infection, with a particular interest in the molecular pathways leading to the development of macrophage and dendritic cell subsets. Dr. Edelson completed the Clinical Pathology Residency Training program in 2009.

  Jeffrey Gordon, MD
      Dr. Robert J. Glaser Distinguished University Professor

      Professor of Developmental Biology and Professor of Medicine
ContactWeb Link

Dr. Gordon joined the LGM Division in 2008. His laboratory characterizes the genomic and metabolic foundations of mutually beneficial relationships between gut microbial communities and their human hosts. Dr. Gordon has a long-standing commitment to creating an interdisciplinary training environment for students and postdocs interested in human microbial ecology and metagenomics. Together with colleagues, he is conducting clinical trials with twins living in developing as well as industrialized countries.

  Ann Gronowski, PhD
      Professor of Pathology and Immunology

      Professor of Obstetrics and Gynecology
ContactWeb Link

Dr. Gronowski joined the LGM Division in 1998. She is the Co-Medical Director of Clinical Chemistry, Serology and Immunology at Barnes-Jewish Hospital, and Co-Director of the Clinical Chemistry Fellowship program. Dr. Gronowskiís research interests are in the development of diagnostic tests to evaluate medical conditions during pregnancy.

  Brenda Grossman, MD
      Associate Professor of Pathology and Immunology
ContactWeb Link

Dr. Grossman joined the LGM Division in 2009. She is currently the Medical Director of Transfusion Medicine Services, which includes the blood bank, apheresis center, cryopreservation laboratory and apheresis consult service. Dr. Grossman is also the Director of the Clinical Pathology Residency program and the Blood Banking and Transfusion Medicine Fellowship program. Dr. Grossmanís research is focused on clinical aspects of transfusion medicine, especially as it applies to transplant patients.

  Malay Haldar, MD PhD
      Instructor of Pathology and Immunology
ContactWeb Link

Dr. Malay Haldar joined the CP Residency program in July 2009. He received his MD degree from the Byramjee Jeejeebhoy Medical College in Pune India after which he entered a PhD Program in Human Genetics at the University of Utah in Salt Lake City. As a resident, Dr. Haldar will be in the Physician Scientist Training Program (PSTP), which places an emphasis on basic research training along with clinical training. In the PSTP, Dr. Haldar plans to continue his research in the area of cancer biology. Dr. Haldar is originally from Bilaspur, India.

  Scott Handley, PhD
      Assistant Professor of Pathology and Immunology
ContactWeb Link

Dr. Handley joined the LGM Division in 2011. He has a background in microbial pathogenesis in the gut and is currently involved in several projects designed to elucidate how the gut microbiome can influence diseases pathology. Dr. Handley is also the Project Manager of the Midwest Regional Center of Excellence for Biodefense and Emerging Infectious Diseases Research (MRCE), which supports research and training programs that contribute to the nationís biodefense and emerging infectious diseases research agenda.

  Ronald Jackups, MD, PhD
      Assistant Professor of Pathology and Immunology

      Assistant Professor of Pediatrics
ContactWeb Link

Dr. Ron Jackups joined the LGM Division in 2012 as the Assistant Director of the Blood Bank and Hematology Laboratory at Barnes-Jewish Hospital. He also serves as the Director of the Blood Bank and Co-Director of the Core Laboratory at St. Louis Childrenís Hospital. Dr. Jackupsí research involves informatics applications to blood banking and hematology including inventory management and education.

  Shashikant Kulkarni, PhD
      Associate Professor of Pathology and Immunology
Associate Professor of Pediatrics
Associate Professor of Genetics

      Head of Clinical Genomics of Genomics and Pathology Services
ContactWeb Link

Dr. Kulkarni joined the LGM Division in 2007. He is the Medical Director of Clinical Cytogenomics and Molecular Pathology. Dr. Kulkarni's principle research interest is to study Chromosomal Structural Variants. His lab uses genome-wide tools for the molecular characterization of these variants associated with human development and cancer. He has clinically validated a "chromosomal- microarray/molecular karyotype" which allows detection of uniparental disomy and copy number changes at kilobase-level, a major Leap forward as compared to the megabase-level resolution for conventional chromosome analysis. He is also the Director of the ABMG Medical Genetics Fellowship program.

  Jack Ladenson, PhD
      Oree M. Carroll and Lillian B. Ladenson Professor of Clinical Chemistry in Pathology and Immunology
ContactWeb Link

Dr. Ladenson joined the LGM Division in 1972. He has served in many key positions including Interim Director From 2003-2008. Dr. Ladensonís laboratory has focused on the development of biomarkers for clinical diagnosis. He developed the quantitative test for CK-MB and the first practical Troponin I assay. His current work involves tests for identifying brain injury such as stroke, Alzheimer's disease, etc. He is also Director of clinical pathology programs for Pathologists Overseas, Inc., an organization dedicated to upgrading clinical diagnostic capability in developing countries.

  Daisy Leung, PhD
      Assistant Professor of Pathology and Immunology

      Assistant Professor of Biochemistry and Molecular Biophysics
ContactWeb Link

Dr. Daisy Leung joined the LGM Division in 2011. Her research interests are in using biochemistry and structural biology to understand regulatory mechanisms of signal transduction pathways at the host-viral interface.

  Christina Lockwood, PhD
      Assistant Professor of Pathology and Immunology

      Co-director of the Molecular Diagnostics Laboratory
ContactWeb Link

Dr. Christina Lockwood joined the LGM division in July 2010. She is the Associate Director of the Molecular Diagnostics Laboratory. Dr. Lockwood's research is focused on the discovery and validation of novel biomarkers of tissue injury. She is investigating the diagnostic utility of specific circulating microRNA molecules as sensitive indicators of neuronal and hepatic injury.

  Leslie McIntosh, PhD
      Assistant Professor of Pathology and Immunology
ContactWeb Link

Dr. McIntosh joined the LGM Division in 2010. She received her PhD in public health epidemiology from St. Louis University in 2008. Her research interests include using technology to translate and disseminate health data; for example, developing on-line and computer aided surveys in order to reduce input errors, decreasing the time to collect survey data, and increasing user accessibility of the survey. She is also interested in developing better ways to improve the presentation of data to end-users and in learning new techniques to analyze data, such as conjoint analysis and social network analysis.

  Yoshiko Mito, PhD
      Assistant Professor of Pathology and Immunology

      Associate Medical Director of Cytogenomics
ContactWeb Link

Dr. Yoshiko Mito joined the LGM Division in February 2013. She is an Associate Director of the Cytogenomics and Molecular Pathology Laboratory. Her research has been focused on studying how genetic and epigenetic information are inherited through cell divisions and regulate the cellular functions. Dr. Mitoís research topics include chromosome segregation, genome-wide profiling of histone variants and allele-specific mapping of chromatin regulators. More recently, she has been investigating the role of epigenetic regulation in human diseases, particularly in cancer progression and resistance to therapies.

  Thalachallour Mohanakumar, PhD
      Jacqueline G. and William E. Maritz Professor of Surgery

      Medical Director of the Histocompatibility Laboratory
ContactWeb Link

Dr. Mohanakumar joined the LGM Division in 1987. He is the Medical Director of Histocompatibility and Immunogenetics Laboratory and Director of the Islet Cell Core Facility. Dr. Thalachallourís research is focused on the role of MHC in transplantation and various disease states, including auto-immunity and cancer.

  Nima Mosammaparast, MD, PhD
      Assistant Professor of Pathology and Immunology
ContactWeb Link

Dr. Mosammaparast joined the LGM division in 2012. He was a resident in clinical pathology at Brigham and Women's Hospital and did postdoctoral work at Harvard Medical School. His research interests lie at the interface of DNA repair and chromatin biology using biochemical and molecular techniques to understand the mechanisms used by mammalian cells to repair their genomes in the chromatin context.

  Rakesh Nagarajan, MD, PhD
      Associate Professor of Pathology and Immunology

      Associate Professor of Genetics
ContactWeb Link

Dr. Nagarajan joined the LGM Division in 2003. He is Director of the Neuroscience Blueprint Biomedical Informatics Core and Director of the Clinical and Translational Science Award Biomedical Informatics Program. Dr. Nagarajanís laboratory focuses on clinical and biomedical informatics research; development of software applications, which will simultaneously co-analyze and co-visualize functional genomics datasets, gene annotation, and clinicopathological data; and utilization of these heuristic algorithms in order to identify potential diagnostic markers and putative therapeutic targets.

  Eugene Oltz, PhD
      Professor of Pathology and Immunology
ContactWeb Link

Dr. Eugene Oltz joined the LGM Division in 2009. His laboratory is focused on the biology of chromatin and how modifications in chromatin can contribute to cellular transformation. Dr. Oltzís lab has been a leader in our understanding of how specific histone modifications are generated and how they can regulate gene transcriptions and programmed gene rearrangements.

  Bijal Parikh, MD, PhD
      Instructor of Pathology and Immunology
ContactWeb Link

Dr. Bijal Parikh entered the Clinical Pathology Residency program in 2007 after receiving MD and PhD degrees from Robert Wood Johnson Medical School/Rutgers University in Piscataway New Jersey. Originally from New Jersey, he is currently focusing his clinical interests in the Molecular Diagnostics Laboratory. Dr. Parikhís current research involves investigating virus-host interactions in the laboratory of Dr. Wayne Yokoyama.

  Jacqueline Payton, MD, PhD
      Assistant Professor of Pathology and Immunology

      Co-director of Molecular Diagnostics
ContactWeb Link

Dr. Payton joined the LGM Division in 2008. She is the Medical Director of Molecular Diagnostics and Associate Director for Bioinformatics. Dr. Paytonís research interests are in the development of genomic and epigenomic tests applicable to a wide variety of diseases. She completed Washington University School of Medicineís Clinical Pathology Residency program where she served as Chief Resident.

  Mitchell Scott, PhD
      Professor of Pathology and Immunology

      Medical Co-Director of Clinical Chemistry
ContactWeb Link

Dr. Scott joined the LGM Division in 1987. He is Co-Director of the Clinical Chemistry Fellowship program and Co-Medical Director of the Clinical Chemistry Laboratory. In addition, Dr. Scott is Director of LGM Medical Student Education. Dr. Scottís research interests focus on clinical chemistry test development in the areas of electrolytes and blood gas evaluation, and in the in area of diagnostic immunoassays.

  Karen Seibert, PhD
      Professor of Pathology and Immunology

      Professor of Genetics
ContactWeb Link

Dr. Karen Seibert is currently Professor of Pathology and Immunology at Washington University School of Medicine. Her work is focused on identifying clinical and translational research programs that have significant potential to lead to improvements in diagnosis or treatment of disease. Previously, Dr. Seibert spent nearly twenty years in the pharmaceutical industry, most recently as Vice President of Research for Pfizer at the St. Louis Laboratories. Her responsibilities included the management of research programs at multiple stages, spanning early new target identification to defining clinical proof of concept as it relates to multiple patient populations. While at Pfizer, Dr. Seibert collaborated with leaders at Washington University to renew the long-standing Biomedical Agreement between the two institutions. She continues as a leader of the collaboration's Joint Steering Committee.

  Joshua Swamidass, MD, PhD
      Assistant Professor of Pathology and Immunology

      Assistant Professor of of Biomedical Engineering
ContactWeb Link

Dr. Swamidass joined the LGM Division in 2009 as a Laboratory Medicine resident and then as an instructor in 2010. Combining math, chemistry, and medicine, Dr. Swamidass' group is focused on designing and applying new computational methods to discover new medicines and improve patient care.

  David Wang, PhD
      Associate Professor of Molecular Microbiology

      Associate Professor of Pathology and Immunology
ContactWeb Link

Dr. Wang joined the LGM Division in 2004. Dr. Wang is one of the Burroughs Wellcome Fund Investigators in the Pathogenesis of Infectious Disease. His laboratory focuses on identifying and characterizing novel viruses responsible for human diseases. To this end, they integrate a variety of experimental methodologies that cross many disciplines including molecular biology, virology, genomics, epidemiology and bioinformatics.

  Mark Watson, MD, PhD
      Associate Professor of Pathology and Immunology
ContactWeb Link

Dr. Watson joined the LGM Division in 1996. Dr. Watsonís laboratory is focused on the use of gene expression and 'next-generation' genomic technologies to identify and validate biomarkers that predict metastatic behavior and therapeutic vulnerability in breast and lung cancer patients.

  Guoyan Zhao, PhD
      Assistant Professor of Pathology and Immunology
ContactWeb Link

Dr. Guoyan Zhao joined the LGM Division in 2007. She is the supervisor of the Pathogen Discovery Facility. The focus of the Pathogen Discovery Facility is the identification of new agents of human disease. Dr. Zhao's group applies cutting edge next-generation sequencing technology and computational analysis to identify novel as well as known viruses from patient specimens.